The GOAT ANTI HUMAN CD192 (N-TERMINAL) Antibody from MyBioSource.com is a Goat Polyclonal antibody to CCR2, CCR2A, and CD192. This antibody recognizes Human antigen. The GOAT ANTI HUMAN CD192 (N-TERMINAL) Antibody has been validated for the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
Goat anti Human CD192 antibody recognizes an epitope within the N-terminal (NT) region of human CD192, otherwise known as CCR2 (C-C chemokine receptor type 2), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, which acts as a receptor for the chemokines MCP-1 (monocyte chemoattractant protein 1), MCP-3 and MCP-4. Interaction between CD192 and MCP-1 initiates chemotactic responses, through an increase in intracellular calcium levels. CD192 acts as a co-receptor with CD4 for HIV1 infection, and variations in CD192 are associated with relative resistance to HIV1